Office profile
Amgen Headquarters & offices · Thousand Oaks, California
Amgen · Thousand Oaks, California
Two paid company-wide shutdown weeks every July and December, on a campus that grew from half a building into more than a million square feet.
The campus, the time off and 45 years in one city — then the pay. Every number from Amgen's own filings, careers site, history pages and its architects' project pages.
- 2 weekspaid company shutdowns a year (U.S.)
- ½ → 1M+sq ft at HQ, 1980 → 1992
- 31,500staff in 50+ countries
- $154,123median employee pay
Sources: careers.amgen.com (Work-Life Balance) · Amgen History (amgen.com) · Form 10-K 2025 · Proxy statement 2026
Companies / United States / Biotechnology / Amgen
THE HEADQUARTERS · ONE AMGEN CENTER DRIVE
A former industrial park turned into a walkable biotech campus
Amgen began in a single building in Thousand Oaks and bought neighbouring properties as they came up. Its architects, Johnson Fain, made the campus about “the spaces in between”: a central meadow, plazas, water features and paths, with cars moved to perimeter parking structures so about 5,000 people walk or take shuttles around a park-like site with views of the coastal mountains. PEI Architects designed the executive offices around a two-storey glass atrium under a skylight.
- 120-acre site
- Master plan: Johnson Fain
- Landscape: Studio-MLA
- Executive offices: PEI Architects
- ≈ 5,000 people on campus
- Childcare and fitness center on site
The campus and its open spaces
Johnson Fain made the campus about the spaces in between, with a central meadow, plazas, water features and paths, and cars moved to perimeter parking structures.
Executive offices (PEI Architects, 2002)
PEI Architects designed the executive offices, 64,992 sq ft completed in 2002, around a two-storey glass atrium under a skylight.
Workplaces and shared rooms
About 5,000 people work on the 120-acre campus, which also has childcare and a fitness center on site.
Facts: Johnson Fain project pages “Amgen” (architecture; urban design) · Studio-MLA project page “Amgen Headquarters” · PEI Architects project page “Amgen Headquarters”. Johnson Fain's text says 130 acres; its facts table says 120 acres.
One campus in Thousand Oaks
| Building | Address |
|---|---|
| Corporate headquarters | One Amgen Center Drive, Thousand Oaks, CA 91320 |
Source: Form 10-K 2025 cover page · See them on the map ↓
Source: Johnson Fain, PEI Architects, Studio-MLA, Clark Pacific and RDH project pages · Amgen press release (Sep 2, 2025) and story (Oct 31, 2025)
Office tour videos
Benefits (United States)
A paid, non-PTO week off every July and every December in U.S. offices.
A PTO program on top of the shutdown weeks.
401(k) with a company match, plus Retiree Medical Savings Accounts.
Amgen products are covered at 100% with an Anthem medical plan.
Employee Stock Purchase Plan (U.S. only), and most staff are eligible for equity awards.
On-site child care in some locations, adoption support, and tutoring and college-admissions help for children.
On-site fitness facility in some locations, or reimbursed or discounted local gyms.
Employee volunteer program and company donation matching.
Source: careers.amgen.com (Benefits; Work-Life Balance) · Form 10-K 2025, Human Capital Resources. Exact match rates and leave lengths are not published on the public site.
Why people stay: what Amgen itself says
Amgen says it continues to see overall low turnover rates; engagement scores were above market benchmarks in 2025.
Paid, non-PTO weeks off for U.S. offices, on top of the PTO already accrued.
A flexible workspace initiative lets many employees agree the work location with their manager.
Access to more than 20 ERGs, plus a mentor program, service awards and tuition reimbursement.
A global talent marketplace lets staff take on work outside their core role to build skills and networks.
An Apprenticeship Program since 2023 hires and trains people without four-year degrees, including an 18-month manufacturing track in North Carolina.
Source: Form 10-K 2025, Human Capital Resources · careers.amgen.com (Benefits, Work-Life Balance)
Who works here
staff members (Dec 31, 2025)
countries
people, 1980 → 2025
employee resource groups
Source: Form 10-K 2025 (U.S. figure = total minus staff outside the U.S.) · Amgen History · careers.amgen.com
Pay at Amgen
Based on all staff worldwide as of December 31, 2025. The CEO earned 160 times this amount.
Source: Proxy statement (DEF 14A), April 7, 2026
Source: Amgen job postings R-254524 (Scientist, Sep 2026) and R-254622 (Senior Scientist – Targeted Protein Degradation, Sep 2026), careers.amgen.com. Base salary only; bonus and stock-based incentives are on top.
Amgen doesn't publish pay by age. Pay by level, above, is the closest official number.
Office history: 45 years, one city — from half a building to a campus
- 1980 Half a shared building — “Building 1”
AMGen (Applied Molecular Genetics) was founded in Thousand Oaks on April 8, 1980, with a staff of three in a shared building now called “Building 1”. First CEO George Rathmann worked from a small trailer to leave space for the scientists.
Source: Amgen History (amgen.com)
No free-to-use photo found yet.Have one? We’d love to add it. - 1982 Laboratory bays in Building 2
A 1982 company photo shows CEO George Rathmann in one of the laboratory bays of Building 2. In those first years AMGen's scientists tried everything from oil-extracting organisms to indigo dye made in E. coli.
Source: Amgen History (amgen.com), 1980 entries and 1982 photo caption
No free-to-use photo found yet.Have one? We’d love to add it. - 1988 A 24,000 sq ft manufacturing plant
Amgen finished a new 24,000 sq ft (≈ 2,230 m²) manufacturing facility as it prepared to launch EPOGEN. Staff numbered 344.
Source: Amgen History (amgen.com)
No free-to-use photo found yet.Have one? We’d love to add it. - 1992 More than a million square feet
From half a building in 1980, the Thousand Oaks headquarters had become a sprawling campus with well over a million sq ft (≈ 92,900 m²). Local papers called the area “perpetually under construction”; staff reached 3,396 by 1994.
Source: Amgen History (amgen.com)
No free-to-use photo found yet.Have one? We’d love to add it. - 1994–95 A master plan for the spaces in between
Johnson Fain began designing at Amgen Center in 1994, turning an opportunistically assembled former industrial park into a walkable, landscaped campus with plazas, a central meadow and perimeter parking.
Source: Johnson Fain project pages · Studio-MLA project page
No free-to-use photo found yet.Have one? We’d love to add it. - 2002 Forty buildings and new executive offices
Amgen's head office and most of its administration, manufacturing and R&D sat in forty buildings in Thousand Oaks (36 owned, 4 leased). PEI Architects completed 64,992 sq ft (6,038 m²) of executive offices around a glass atrium.
Source: Form 10-K 2002, Item 2 · PEI Architects project page
No free-to-use photo found yet.Have one? We’d love to add it. - 2025 Breaking ground on a $600 million science center
Amgen broke ground on a new center for science and innovation at its Thousand Oaks headquarters, bringing R&D and Process Development together. It is designed to meet LEED Gold and to be the most sustainable building on the campus.
Source: Amgen press release (Sep 2, 2025) · Amgen story (Oct 31, 2025) · Form 10-K 2025
No free-to-use photo found yet.Have one? We’d love to add it.
Map: how the headquarters moved
Amgen has never left Thousand Oaks. It started in one building and bought the neighbouring properties as they came up, so the whole story fits on one campus.
- 1 · 1980Building 1, Thousand Oaks — Founded with a staff of three in a shared building that became the seed of the campus
- 2 · 1992Amgen Center, Thousand Oaks — Well over a million sq ft on the growing campus
- 3 · TodayOne Amgen Center Drive — Corporate headquarters; a $600M science center under construction
Addresses: Form 10-K 2025 cover · Amgen History · Johnson Fain project page (campus grew from a single building) · Location: OpenStreetMap
What Amgen does
Amgen discovers, develops, makes and delivers medicines made from living cells (biologics) for serious illnesses — cancer, heart disease, osteoporosis, inflammatory and rare diseases. It helped start the biotechnology industry in 1980.
One operating segment: human therapeutics.
Where the money came from · biggest products by sales, 2025
Source: Form 10-K 2025, product sales by product and Item 1 (business, segment)
Source: Form 10-K 2025 · per-employee figure and share calculated by eciffo
Growth: revenue vs. people
$14.8B → $36.8B
17,500 → 31,500
Calendar years. Revenue: SEC XBRL financial data from Amgen's 10-K filings. Staff: Form 10-K, approximate year-end counts. Multiples calculated by eciffo.
Chief executives
Chairman and CEO. Joined Amgen in 2006; CFO 2007–2010, President since 2010, Chairman since 2013.
Amgen's third CEO; formerly President and COO.
Promoted from CFO; led the launches of EPOGEN and NEUPOGEN.
First CEO, nicknamed “Mr. Biotech”.
Founded on April 8, 1980 as Applied Molecular Genetics, the brainchild of venture capitalist William K. (Bill) Bowes and associates.
Source: Form 10-K 2025 (executive officers) · Amgen History (amgen.com)
Amgen: questions people ask
Where is Amgen's headquarters?
At One Amgen Center Drive in Thousand Oaks, California, part of the greater Los Angeles region. Amgen has been headquartered there since it was founded in 1980.
Source: Form 10-K 2025 · Amgen press release, Sep 2, 2025
Who designed Amgen's Thousand Oaks campus?
Johnson Fain has planned and designed buildings and interiors on the campus since 1994, with Studio-MLA on the landscape master plan. PEI Architects designed the executive offices, completed in 2002.
Source: Johnson Fain, Studio-MLA and PEI Architects project pages
How big is Amgen's headquarters campus?
Johnson Fain lists a 120-acre site (its project text says 130 acres). Amgen says the campus already had well over a million sq ft by 1992; in 2002 it covered forty buildings.
Source: Johnson Fain project page · Amgen History · Form 10-K 2002
What is Amgen building in Thousand Oaks now?
A $600 million center for science and innovation, which broke ground in October 2025. It brings R&D and Process Development together and is designed to meet LEED Gold.
Source: Amgen press release (Sep 2, 2025) · Amgen story (Oct 31, 2025)
How many people work at Amgen?
About 31,500 staff members in more than 50 countries at the end of 2025, about 13,000 of them outside the United States.
Source: Form 10-K 2025
What benefits does Amgen offer?
In the U.S.: two paid company shutdown weeks (July and December) on top of PTO, a 401(k) with company match, an employee stock purchase plan, Amgen medicines covered at 100% on Anthem plans, on-site childcare and fitness centers at some sites, and donation matching.
Source: careers.amgen.com
Does Amgen allow remote or hybrid work?
Amgen runs a flexible workspace initiative: many employees agree with their manager where they work best, supporting both virtual and in-person work. Each job posting states its work location type.
Source: Form 10-K 2025 · Amgen job postings
How much do Amgen employees make?
The median staff member's total compensation was $154,123 in 2025. 2026 Thousand Oaks postings list $115,393–$156,121 for a Scientist and $127,122–$171,988 for a Senior Scientist.
Source: Proxy statement 2026 · job postings R-254524 and R-254622
Who is Amgen's CEO?
Robert A. Bradway, CEO since 2012 and Chairman since 2013. He is Amgen's fourth CEO, after George Rathmann, Gordon Binder and Kevin Sharer.
Source: Form 10-K 2025 · Amgen History
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Amgen's official social accounts
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